Weinmaster G, Fischer JA. (2011) Notch ligand ubiquitylation: What is it good for? Developmental Cell, in press
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Banks SM, Cho B, Eun SH, Lee J-H, Windler SL, Xie X, Fischer JA (2011) The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in Notch signaling cells is not recycling. PLoS One: e18259
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Cho B, Fischer JA (2011) Ral GTPase promotes asymmetric Notch activation in response to Frizzled/PCP signaling by repressing ligand-independent receptor activation. Development 138: 1349-1359
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Kracklauer MP, Wiora HM, Chen X, Deery WJ, Bolival Jr II B, Romanowicz D, Simonette RA, Fuller MT, Fischer JA (2010) The Drosophila SUN protein Dspag4 cooperates with Yuri Gagarian to position the basal body on the spermatid nucleus. Journal of Cell Science 123: 2763-2772 (featured on cover)
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Lee JH, Overstreet E, Fitch E, Fleenor S, Fischer JA (2009) Drosophila liquid facets-Related encodes Golgi epsin and is an essential gene required for cell proliferation, growth, and patterning. Developmental Biology 331: 1-13
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Perdigoto CNLR, Gervais L, Overstreet E, Fishcer JA, Guichet A, Schweisguth F (2008) Overexpression of Partner of Numb induces asymmetric distribution of the P14P 5-kinase Skittles in mitotic sensory organ precursor cells in Drosophila. PLoS ONE 3(8)e3072
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Wu Y, Bolduc F, Bell K, Tully T, Fang Y Sehgal A, Fischer JA (2008) A Drosophila model for Angelman syndrome. Proceedings of the National Academy of Sciences, USA 105(34):12399-404
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Xie X, Fischer JA (2008) On the functions of the Drosophila KASH proteins Msp-300 and Klarsicht (2008) FLY 2:74-81
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Eun SH, Banks SML, Fischer JA (2008) Auxilin is essential for Delta signaling. Development 135:1089-1095.
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Kracklauer M, Banks S, Xie X, Fischer JA (2007) Drosophila klaroid encodes a SUN domain protein required for Klarsicht localization to the nuclear envelope and nuclear migration in the eye. FLY1:75-85 (featured on cover)
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Eun SH, Lea K, Overstreet E, Stevens S, Lee J-H, Fischer JA. (2007) Identification of genes that interact with Drosophila liquid facets. Genetics 175:1163-1174
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Fischer JA, Eun SH, Doolan B. (2006) Endocytosis, endosome trafficking and the regulation of Drosophila development. Annual Review of Cell and Developmental Biology 22:181-206
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Starr DA, Fischer JA (2005) KASH 'n Karry: the KASH domain family of cargo-specific cytoskeletal adaptor proteins. Bioessays 27:1136-1146
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Fischer JA, Acosta S, Kenny A, Robinson C, Cater C, Hook J (2004) Drosophila Klarsicht has distinct domains for nuclear envelope and microtubule localization in the eye. Genetics 168:1382-1393.
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Overstreet E, Fitch E, Fischer JA (2004) Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells. Development 131:5355-5366.
commentaries on this paper:
- Highlighted in "In this issue" in Development.
- Featured in Science STKE (http://www.stke.org) as a noteworthy contribution to the scientific literature in "This Week in Signal Transduction."
- Featured in : Kanwar and Fortini (2004) Notch Signaling: A different sort makes the cut. Current Biology 14:R1043-R1045.
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Patterson K, Molofsky A, Robinson, C, Acosta, S, Cater C, Fischer JA (2004) The roles of Klarsicht, lamin, and the MTOC in developmentally regulated migration of photoreceptors in the Drosophila eye. Molecular Biology of the Cell 15: 600-610. Published on-line November 2003.
Featured on March 2004 cover and on the ASCB Meeting (12/03) T-shirt!
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Fischer JA (2003) Deubiquitinating enzymes: their roles in development, differentiation, and disease. International Review of Cytology 229:43-72.
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Overstreet E, Chen X, Wendland B, Fischer JA (2003) Either part of a Drosophila epsin (Liquid facets) protein, divided after the ENTH domain, functions in the internalization of Delta in the developing eye. Current Biology 13:854-860.
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Fischer JA (2003) The role of molecular motors in generating developmental asymmetry. In Molecular Motors, ed. M. Schliwa, Wiley-VCH. Chapter 15, pp. 357-376.
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Fischer JA , Overstreet E (2002) Fat facets does a Highwire act at the synapse. Bioessays 24:13-16.
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Chen X, Zhang B, Fischer, JA (2002) A specific protein substrate for a deubiquitinating enzyme: Liquid facets is the substrate of Faf facets. Genes and Development 16: 289-294.
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Chen X, Fischer JA (2002) A P element transformation vector for high levels of gene expression in the germ-line cells of the ovary and undifferentiated cells in the Drosophila eye. Plasmid 47: 61-65.
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Fischer JA (2001) Developmental regulation through protein stability. In Results and Problems in Cell Differentiation (Vol. 37): Drosophila eye development. ed. K. Moses. Springer-Verlag. pp. 151-167
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Fischer JA (2000) Molecular motors and developmental asymmetry. Current Opinion in Genetics and Development 10:489-496.
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Chen X, Fischer JA (2000) In vivo structure/function analysis of the Drosophila fat facets deubiquitinating enzyme gene. Genetics 156:1829-1836.
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Chen X, Li Q, Fischer JA (2000) Genetic analysis of the Drosophila DNAprim gene: the function of the 60 kD primase subunit of DNA polymerase opposes the fat facets signaling pathway in the eye. Genetics 156:1787-1795.
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Chen X, Overstreet E, Wood SA, Fischer JA (2000) On the conservation of function of the Drosophila Fat facets deubiquitinating enzyme and Fam, its mouse homolog. Development Genes and Evolution 210: 603-610.
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Cadavid ALM, Ginzel A, Fischer JA (2000) The function of the Drosophila Fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis. Development 127: 1727-1736.
commentaries on this paper:
- Carthew RW, Xu C (2000) Endocytosis: why wait to deubiquitinate? Current Biology 10:R532-R534.
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Wu Z, Li Q, Fortini M, Fischer JA. (1999) Genetic analysis of the role of the Drosophila fat facets gene in the ubiquitin pathway. Developmental Genetics 25: 312-320.
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Mosley-Bishop KL, Li Q, Patterson K, Fischer JA (1999) Molecular analysis of the klarsicht gene and its role in nuclear migration within differentiating cells of the Drosophila eye. Current Biology 9: 1211-1220.
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Li Q, Hariharan IK, Chen F, Huang Y, Fischer JA (1997) Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets gene in Drosophila eye development. Proceedings of the National Academy of Sciences, USA 94: 12515-12520.
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Fischer JA, Leavell SK, Li Q (1997) Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development. Developmental Genetics 21: 167-174. **featured on cover**
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Huang Y, Fischer-Vize JA (1996) Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets deubiquitinating enzyme. Development 122: 3207-3216.
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Huang Y, Baker RT, Fischer-Vize JA (1995) Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science 270: 1828-1831.
commentaries on this paper:
- Kalderon D (1996) Protein degradation: de-ubiquitinate to decide your fate. Current Biology 6: 662-665.
- Hopkin K (1997) Regulating cellular processes: the power of protein degradation. Journal of NIH Research 9: 36-42. **our work featured on cover**
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Fischer-Vize JA and Mosley, KL (1994) marbles mutants: uncoupling cell determination and nuclear migration in the developing Drosophila eye. Development 120: 2609-2618.
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Some of Janice's publications as postdoc and graduate student: |
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Fischer-Vize JA, Rubin GM, Lehmann R (1992) The fat facets gene is required for Drosophila eye and embryo development. Development 116: 985-1000. **featured on cover**
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Fischer-Vize JA, Vize PD, Rubin GM (1992) A unique mutation in the Enhancer of split gene complex affects the fates of the mystery cells in the developing Drosophila eye. Development 115: 89-101.
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Falb D, Fischer J, Maniatis T (1992) Rearrangement of upstream regulatory elements leads to ectopic expression of the Drosophila mulleri Adh-2 gene. Genetics 132: 1071-1079.
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Fischer JA, Giniger E, Maniatis T, Ptashne M (1988) GAL4 activates transcription in Drosophila. Nature 332: 853-856.
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Fischer JA, Maniatis T (1988) Drosophila Adh: A promoter element expands the tissue specificity of an enhancer. Cell 53: 451-461.
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Maniatis T, Goodbourn S, Fischer JA (1987) Regulation of inducible and tissue-specific gene expression. Science 236:1237-1245.
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Fischer JA, Maniatis T (1986) Regulatory elements involved in Drosophila Adh gene expression are conserved in divergent species and separate elements mediate expression in different tissues. EMBO Journal 5: 1275-1289.
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