OCHMAN LAB
People
Ph.D student
Angela O'Donnell
Microbiology
Angela is broadly interested in discovering and engineering new antimicrobials. She is also interested in exploring how the study of antimicrobial evolution can inform and guide research. Angela is co-advised by Howard Ochman and Bryan Davies.
Academic history
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Ph.D. student, Microbiology, University of Texas at Austin, 2020 - present
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B.A., Biology, Smith College (Northampton, MA), 2018
Professional History
• Research Assistant, Integrative Biology, University of Texas at Austin, 2018 - 2020
Publications
O’Donnell AC, Wang X, Kadeřábková N, Groover KE, Perez BC, Helms A, Brodbelt JS, Mavridou DAI, Davies BW. 2025. Resurfacing promotes antibacterial activity of a lipid A–binding nanobody. Proc. Natl. Acad. Sci. U.S.A. 122 (36) e2509305122, https://doi.org/10.1073/pnas.2509305122.
Parker JK, Feller AL, Gu R, Sanchez-Paiva S, Perez BC, O'Donnell AC, Deng W, Ousterhout RM, Kim SY, Wilke CO, Davies BW. 2025. Antibacterial microcins are ubiquitous and functionally diverse across bacterial communities. Nat Commun. 16(1):6048. doi: 10.1038/s41467-025-61151-z.
Randall JR, Groover KE, O'Donnell AC, Garza JM, Cole TJ, Davies BW. 2023. Adapting antibacterial display to identify serum-active macrocyclic peptide antibiotics. PNAS Nexus 2(8):pgad270. doi: 10.1093/pnasnexus/pgad270.
Knauf GA, Groover KE, O'Donnell AC, Davies BW. 2023. Generation of Synthetic Acinetobacter baumannii-Specific Nanobodies. ACS Infect Dis .9(6):1190-1195. doi: 10.1021/acsinfecdis.3c00024.
Randall JR, Wang X, Groover KE, O'Donnell AC, Davies BW. 2023. Using display technologies to identify macrocyclic peptide antibiotics. Biochim Biophys Acta Mol Cell Res. 870(5):119473. doi: 10.1016/j.bbamcr.2023.119473
Li Y, O'Donnell AC, Ochman H. 2021. Discriminating arboviral species. J Gen Virol. 102(4). doi: 10.1099/jgv.0.001572
Bobay LM, O'Donnell AC, Ochman H. 2021. Recombination events are concentrated in the spike protein region of Betacoronaviruses. PLoS Genet. 16(12):e1009272. doi: 10.1371/journal.pgen.1009272.
Motta EVS, Mak M, De Jong TK, Elijah Powell J, O'Donnell A, Suhr KJ , Riddington IM, and Moran NA. 2020. Oral or topical exposure to glyphosate in herbicide formulation impacts the gut microbiota and survival rates of honey bees. Appl Environ Microbiol. 86(18):e01150-20. doi: 10.1128/AEM.01150-20.