Nancy A. Moran's lab

About Nancy Moran

Nancy Moran

Nancy A. Moran

Warren J. and Viola Mae Raymer Chair Professor
Integrative Biology
University of Texas at Austin

nancy.moran@austin.utexas.edu

download CV (pdf)


Schizaphis graminum winged aphid

Research

My long-term interests are in the evolution of biological complexity, such as that apparent in complex life histories, in intimate interactions among species, and in species-diversity of clades and communities.

My focus is on symbiosis, particularly that between multicellular hosts and microbes.

Education

  • B.A. Highest Honors, Biology, 1976 University of Texas
  • M.S., Zoology, 1978 University of Michigan
  • Ph.D., Zoology, 1982 University of Michigan (Dissertation advisors: William D. Hamilton and Richard D. Alexander)

Professional Experience

  • National Acad. Sciences Fellow, 1984, Inst. of Entomology,  Czechoslovakia
  • Postdoctoral Fellow, 1984-86, Northern Arizona University
  • Assistant Professor, 1986-91, University of Arizona
  • Associate Professor, 1991-96, University of Arizona
  • Professor, 1996-2000, University of Arizona
  • Regents’ Professor, 2000-2010, University of Arizona
  • William H. Fleming Professor, May 2010-2013, Yale University
  • Professor, 2013- , The University of Texas at Austin
  • Leslie Surginer Endowed Professor, 2014-2017, The University of Texas at Austin
  • Warren J. and Viola Mae Raymer Chair Professor, 2018- , The University of Texas at Austin

Publications (last two years)

Full publication list (website) | Google Scholar page

Hammer TJ, Easton-Calabria A, Moran NA. 2022. Microbiome assembly and maintenance across the lifespan of bumble bee workers. Mol Ecol . 2022 Nov 5. doi: 10.1111/mec.16769. [Online ahead of print.]

Li Z, Li Y, Xue AZ, Dang V, Renee Holmes V, Spencer Johnston J, Barrick JE, Moran NA. 2022. The genomic basis of evolutionary novelties in a leafhopper. Mol Biol Evol . 39(9):msac184. doi: 10.1093/molbev/msac184.

Holley JC, Jackson MN, Pham AT, Hatcher SC, Moran NA. 2022. Carpenter Bees (Xylocopa) Harbor a Distinctive Gut Microbiome Related to That of Honey Bees and Bumble Bees. Appl Environ Microbiol. 88(13):e0020322. doi: 10.1128/aem.00203-22.

Smith TE, Li Y, Perreau J, Moran NA. 2022. Elucidation of host and symbiont contributions to peptidoglycan metabolism based on comparative genomics of eight aphid subfamilies and their Buchnera. PLoS Genet. 18(5):e1010195. doi: 10.1371/journal.pgen.1010195.

Motta EVS, Powell JE, Leonard SP, Moran NA. 2022. Prospects for probiotics in social bees. Philos Trans R Soc Lond B Biol Sci. 377(1853): 20210156. doi: 10.1098/rstb.2021.0156.

Li Y, Leonard SP, Powell JE, Moran NA. 2022. Species divergence in gut-restricted bacteria of social bees. Proc Natl Acad Sci U S A . 119(18):e2115013119. doi: 10.1073/pnas.2115013119.

Nakabachi A, Moran NA. 2022. Extreme polyploidy of Carsonella, an organelle-like bacterium with a drastically reduced genome. Microbiol Spectr.10(3):e0035022. doi: 10.1128/spectrum.00350-22

Busby TJ, Miller CR, Moran NA, Van Leuven JT. 2022. Global Composition of the Bacteriophage Community in Honey. mSystems Bees.26;7(2):e0119521. doi: 10.1128/msystems.01195-21

Motta EVS, Powell JE, Moran NA. 2022. Glyphosate induces immune dysregulation in honey bee. Anim Microbiome 4(1):16. doi: 10.1186/s42523-022-00165-0

Blaxter M, Archibald JM, Childers AK, Coddington JA, Crandall KA, Di Palma F, Durbin R, Edwards SV, Graves JAM, Hackett KJ, Hall N, Jarvis ED, Johnson RN, Karlsson EK, Kress WJ, Kuraku S, Lawniczak MKN, Lindblad-Toh K, Lopez JV, Moran NA, Robinson GE, Ryder OA, Shapiro B, Soltis PS, Warnow T, Zhang G, Lewin HA. 2022. Why sequence all eukaryotes? Proc Natl Acad Sci U S A. 119(4):e2115636118. doi: 10.1073/pnas.2115636118

Perreau J, Moran NA. 2022. Genetic innovations in animal-microbe symbioses. Nat Rev Genet. 23(1): 23-39. doi: 10.1038/s41576-021-00395-z.

Moran NA. 2021. Microbe profile: Buchnera aphidicola: ancient aphid accomplice and endosymbiont exemplar. Microbiology (Reading). 167(12). doi: 10.1099/mic.0.001127

Smith TE, Lee M, Person MD, Hesek D, Mobashery S, Moran NA. 2021. Horizontal-acquisition of a promiscuous peptidoglycan-recycling enzyme enables aphids to influence symbiont cell wall metabolism. mBio. 12(6):e0263621. doi: 10.1128/mBio.02636-21

Hammer TJ, Moran NA. 2021. The gut microbiota of bumblebees. Insectes Soc. 68 (2-3). doi: 10.1007/s00040-021-00837-1

Steele MI, Motta EVS, Gattu T, Martinez D, Moran NA. 2021. The gut microbiota protects bees from invasion by a bacterial pathogen. Microbiol Spectr. 2021 9(2):e0039421. doi: 10.1128/Spectrum.00394-21

Perreau J, Zhang B, Maeda GP, Kirkpatrick M, Moran NA. 2021. Strong within-host selection in a maternally inherited obligate symbiont: Buchnera and aphids. Proc Natl Acad Sci U S A. 118(35):e2102467118. doi: 10.1073/pnas.2102467118

Powell JE, Carver Z, Leonard SP, Moran NA. 2021. Field-realistic tylosin exposure impacts honey bee microbiota and pathogen susceptibility, which is ameliorated by native gut probiotics. Microbiol Spectr. 9(1):e0010321. doi: 10.1128/Spectrum.00103-21.

Cerqueira AES, Hammer TJ, Moran NA, Santana WC, Kasuya MCM, da Silva CC. 2021. Extinction of anciently associated gut bacterial symbionts in a clade of stingless bees. ISME J. 15(9):2813-2816. doi: 10.1038/s41396-021-01000-1.

Steele MI, Moran NA. 2021. Evolution of interbacterial antagonism in bee gut microbiota reflects host and symbiont diversification. mSystems 6(3):e00063-21. doi: 10.1128/mSystems.00063-21

Schepers MJ, Yelland JN, Moran NA, Taylor DW. 2021. Isolation of the Buchnera aphidicola flagellum basal body complexes from the Buchnera membrane. PLoS One 16(5):e0245710. doi: 10.1371/journal.pone.0245710

Perreau J, Patel DJ, Anderson H, Maeda GP, Elston KM, Barrick JE, Moran NA. 2021. Vertical transmission at the pathogen-symbiont interface: Serratia symbiotica and aphids. mBio 12(2):e00359-21. doi: 10.1128/mBio.00359-21

Hammer TJ, Le E, Moran NA. 2021. Thermal niches of specialized gut symbionts: the case of social bees. Proc Biol Sci. 288(1944): 20201480. doi: 10.1098/rspb.2020.1480