Bio344 Molecular Biology

  Overview

The purpose of this course is to provide a reasonably in-depth analysis of the fundamental knowledge and principles upon which molecular biology is based. This analysis will include discussions of key concepts, experiments, techniques, and some of the scientists involved, so that a realistic feel for the area can be gleaned. Mechanisms will be emphasized, since a mechanistic framework is necessary to understand regulation, and how genes have evolved. The main topics are: DNA replication, recombination, repair, and transcription; RNA processing and translation; and selected topics in genomics, genetic engineering, and viruses.                                   

 

Instructors

 

Course Information and Policies

 

Lecture, Text & Exam  Schedule

 

Old Exams

 

Quizzes 

 

Archive of old announcements

 

Molecular Biology Background

 

  Lecture 1:  Intro-History-DNA/RNA Structure 

  Lecture 2:  DNA Replication 1

       QT Movie: DNA polymerization

       QT Movie: Bidirec. replic.

       QT Movie: Helicase action

  Lecture 3:  DNA Replication 2

       QT Movie: Pol III dimer synthesizing both strands      

  Lecture 4:  Chromatin

       QT Movie: DNA Packaging in a cell    

  Lecture 5:  DNA Recombination

       QT Movie: HJ & Branch Migration

       Animation: Holliday recombination

  Lecture 6:  Prokaryotic Transcription 1 

  Lecture 7:  Prokaryotic Transcription 2

  Lecture 8:  Prokaryotic Transcription 3 

  Lecture 9:  Prok. Transcription 4 & Organelle Transcription

  Lecture10: Eukaryotic Transcription 1

Lecture 11: Eukaryotic Transcription 2 

Lecture 12: Eukaryotic Transcription 3

Lecture 13: Eukaryotic Transcription 4

Lecture 14: RNA Splicing 1

      QT Movie: Splicing

 Lecture 15: RNA Splicing 2   

Lecture 16: RNA Capping & PolyA

Lecture 17: RNA Editing   

Lecture 18: Post-transcriptional silencing (RNAi)     

     QT Movie: RNAi

Lecture 19: Translation 1

        Video       Translation Video    

Lecture 20: Translation 2   

  Lecture 21: Genomics  

Lecture 22: Transgenics

Lecture 23: Review  

 

 

Be sure to RELOAD all pages each time you visit this site. These pages will be changed frequently.

This site was last changed on  07/16/2009 

Enamul Huq, Ph.D.

David Herrin, Ph.D.

 

Section of Molecular Cell and Developmental Biology Announcements

July 10- The course information is posted in this web site.

 

 

 


Link to research-related topics in the Huq lab.


Links to research-related topics in the Herrin lab:

MCDB Seminar 2006

CMB Retreat Seminar 2005


 

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